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HDAC ligand

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-132998
    HDAC6 degrader-1

    		PROTACs Others
    HDAC6 degrader-1 is a PROTAC that comprises a selective HDAC6 inhibitor Nexturastat A (Nex A) as the HDAC6 binder, a linker and a ligand for recruiting E3 ligase. HDAC6 degrader-1 induces significant degradation of HDAC6, exhibits excellent selectivity against other HDACs, and demonstrates efficient inhibition of cell proliferation .
    HDAC6 degrader-1
  • HY-131961
    Triciferol

    		VD/VDR HDAC Cancer
    Triciferol functions as a multiple ligand with combined VDR agonist and HDAC antagonist activities. Triciferol binds directly to the VDR (IC50=87 nM), and functions as an agonist with 1,25D-like potency on several 1,25D target genes. Triciferol induces marked tubulin hyperacetylation, and augments histone acetylation. Antiproliferative and cytotoxic activities .
    Triciferol
  • HY-150859
    HDAC ligand-1

    		HDAC Cancer
    HDAC ligand-1 is a HDAC ligand that can be used to synthesize PROTAC HDAC degraders .
    <em>HDAC</em> <em>ligand</em>-1

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